The influence of 2-morpholino-5-(thienyl-2)-6-H-1,3,4-thiadiazine (H-29) on the platelet aggregation has been studied in experiments on donor plasma in vitro. It is established that H-29 causes a decrease in the platelet interaction induced by ADP and arachidonic acid. The influence of H-29 on platelet aggregation was also studied in ex vivo experiments with intravenous and oral administration, and some parameters of plasmatic hemostasis were evaluated.
|Translated title of the contribution||The Antiaggregant Action of 2-Morpholino-5-(thienyl-2)-6H-1,3,4-thiadiazine in In Vitro and Ex Vivo Experiments|
|Number of pages||4|
|Journal||Eksperimental'naya i Klinicheskaya Farmakologiya|
|Publication status||Published - 2013|
Level of Research Output
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