Способ получения парацетамола: патент на изобретение

Translated title of the contribution: METHOD FOR PRODUCING PARACETAMOL: patent of invention

Юрий Алексеевич Азев (Inventor), Кирилл Александрович Чарушников (Inventor), Алексей Михайлович Гибор (Inventor), Ольга Сергеевна Коптяева (Inventor), Василий Алексеевич Бакулев (Inventor)

Research output: Patent

Abstract

FIELD: medicine.
SUBSTANCE: producing paracetamol involves the catalytic hydrogenation of p-nitrosophenol with Pd/C or Ni-Re catalysts at 20-70°C in a combination with acetylation in aqueous ethanol or aqueous isopropanol in the presence of acetic anhydride.
EFFECT: advanced method for producing p-acetylaminophenol using inexpensive solvents and ensuring a high product yield.
Translated title of the contributionMETHOD FOR PRODUCING PARACETAMOL: patent of invention
Original languageRussian
Patent number2574733
IPCC07C 233/25,C07C 231/10
Filing date26/12/2014
Publication statusPublished - 10 Feb 2016

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