Chemoenzymatic Synthesis and Antiherpes Activity of 5-Substituted 4,6-Difluorobenzimidazoles Ribo- and 2′-Deoxyribonucleosides

Maria I. Kharitonova, Ilja V. Fateev, Alexei L. Kayushin, Irina D. Konstantinova, Svetlana K. Kotovskaya, Valeria L. Andronova, Georgii A. Galegov, Valery N. Charushin, Anatoly I. Miroshnikov

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)
Original languageEnglish
Article numberss-2015-t0386-op
Pages (from-to)394-406
Number of pages13
JournalSynthesis (Germany)
Volume48
Issue number3
DOIs
Publication statusPublished - 2 Feb 2016

Fingerprint

Deoxyribonucleosides
Nucleosides
Cytotoxicity
Viruses
Bearings (structural)
Purine-Nucleoside Phosphorylase
Benzimidazoles
Morpholinos
Fluorine
Bioactivity
Benzene
Cell culture
Escherichia coli
Antiviral Agents
Atoms
benzimidazole
Substrates

Keywords

  • drug discovery
  • fluorine
  • herpes simplex virus
  • nucleosides

ASJC Scopus subject areas

  • Organic Chemistry
  • Catalysis

WoS ResearchAreas Categories

  • Chemistry, Organic

Cite this

Kharitonova, M. I., Fateev, I. V., Kayushin, A. L., Konstantinova, I. D., Kotovskaya, S. K., Andronova, V. L., ... Miroshnikov, A. I. (2016). Chemoenzymatic Synthesis and Antiherpes Activity of 5-Substituted 4,6-Difluorobenzimidazoles Ribo- and 2′-Deoxyribonucleosides. Synthesis (Germany), 48(3), 394-406. [ss-2015-t0386-op]. https://doi.org/10.1055/s-0035-1560911
Kharitonova, Maria I. ; Fateev, Ilja V. ; Kayushin, Alexei L. ; Konstantinova, Irina D. ; Kotovskaya, Svetlana K. ; Andronova, Valeria L. ; Galegov, Georgii A. ; Charushin, Valery N. ; Miroshnikov, Anatoly I. / Chemoenzymatic Synthesis and Antiherpes Activity of 5-Substituted 4,6-Difluorobenzimidazoles Ribo- and 2′-Deoxyribonucleosides. In: Synthesis (Germany). 2016 ; Vol. 48, No. 3. pp. 394-406.
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author = "Kharitonova, {Maria I.} and Fateev, {Ilja V.} and Kayushin, {Alexei L.} and Konstantinova, {Irina D.} and Kotovskaya, {Svetlana K.} and Andronova, {Valeria L.} and Galegov, {Georgii A.} and Charushin, {Valery N.} and Miroshnikov, {Anatoly I.}",
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Kharitonova, MI, Fateev, IV, Kayushin, AL, Konstantinova, ID, Kotovskaya, SK, Andronova, VL, Galegov, GA, Charushin, VN & Miroshnikov, AI 2016, 'Chemoenzymatic Synthesis and Antiherpes Activity of 5-Substituted 4,6-Difluorobenzimidazoles Ribo- and 2′-Deoxyribonucleosides' Synthesis (Germany), vol. 48, no. 3, ss-2015-t0386-op, pp. 394-406. https://doi.org/10.1055/s-0035-1560911

Chemoenzymatic Synthesis and Antiherpes Activity of 5-Substituted 4,6-Difluorobenzimidazoles Ribo- and 2′-Deoxyribonucleosides. / Kharitonova, Maria I.; Fateev, Ilja V.; Kayushin, Alexei L.; Konstantinova, Irina D.; Kotovskaya, Svetlana K.; Andronova, Valeria L.; Galegov, Georgii A.; Charushin, Valery N.; Miroshnikov, Anatoly I.

In: Synthesis (Germany), Vol. 48, No. 3, ss-2015-t0386-op, 02.02.2016, p. 394-406.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Chemoenzymatic Synthesis and Antiherpes Activity of 5-Substituted 4,6-Difluorobenzimidazoles Ribo- and 2′-Deoxyribonucleosides

AU - Kharitonova, Maria I.

AU - Fateev, Ilja V.

AU - Kayushin, Alexei L.

AU - Konstantinova, Irina D.

AU - Kotovskaya, Svetlana K.

AU - Andronova, Valeria L.

AU - Galegov, Georgii A.

AU - Charushin, Valery N.

AU - Miroshnikov, Anatoly I.

PY - 2016/2/2

Y1 - 2016/2/2

KW - drug discovery

KW - fluorine

KW - herpes simplex virus

KW - nucleosides

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U2 - 10.1055/s-0035-1560911

DO - 10.1055/s-0035-1560911

M3 - Article

VL - 48

SP - 394

EP - 406

JO - Synthesis (Germany)

JF - Synthesis (Germany)

SN - 0039-7881

IS - 3

M1 - ss-2015-t0386-op

ER -