Competitive routes to cyclizations of polyfluoroalkyl-containing 2-tolylhydrazinylidene-1,3-diketones with 3-aminopyrazoles into bioactive pyrazoloazines

Natalia A. Elkina, Yanina V. Burgart, Evgeny V. Shchegolkov, Olga P. Krasnykh, Vera V. Maslova, Galina A. Triandafilova, Sergey S. Solodnikov, Anna A. Muryleva, Maria A. Misiurina, Alexander V. Slita, Vladimir V. Zarubaev, Victor I. Saloutin

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)
Original languageEnglish
Article number109648
Number of pages11
JournalJournal of Fluorine Chemistry
Volume240
DOIs
Publication statusPublished - Dec 2020

Keywords

  • 3-Aminopyrazoles
  • Analgesic and antiviral activities
  • Haloformic cleavage
  • N,N- and C,N-cyclization
  • Polyfluoroalkyl-containing 2-tolylhydrazinylidene-1,3-diketones
  • Pyrazolo[1,5-a]pyrimidines
  • Pyrazolo[3,4-b]pyridines
  • Toxicity
  • Pyrazolo[3,4-b] pyridines
  • DESIGN
  • ALPHA-AMINOAZOLES
  • DISCOVERY
  • PYRAZOLOPYRIDINE DERIVATIVES
  • POTENT
  • HETEROCYCLES
  • GROWTH
  • BIOLOGICAL EVALUATION
  • INHIBITORS
  • ANTAGONISTS

ASJC Scopus subject areas

  • Biochemistry
  • Inorganic Chemistry
  • Physical and Theoretical Chemistry
  • Environmental Chemistry
  • Organic Chemistry

WoS ResearchAreas Categories

  • Chemistry, Inorganic & Nuclear
  • Chemistry, Organic

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