Novel α-Aminophosphonates of imatinib Intermediate: Synthesis, anticancer Activity, human Abl tyrosine kinase Inhibition, ADME and toxicity prediction

Saikiran Aita, Vishnu Nayak Badavath, Mohan Gundluru, Murali Sudileti, Bakthavatchala Reddy Nemallapudi, Sravya Gundala, Grigoriy Vasilievich Zyryanov, Naga Raju Chamarti, Suresh Reddy Cirandur

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)
Original languageEnglish
Article number104718
Number of pages11
JournalBioorganic Chemistry
Volume109
DOIs
Publication statusPublished - Apr 2021

Keywords

  • Abl1 Tyrosine kinase inhibitor
  • Cytotoxic agents
  • Docking studies
  • Drug-likenes prediction
  • Kabachnik-Fields reaction
  • NiO nanoparticles
  • α-Aminophosphonates of Imatinib
  • alpha-Aminophosphonates of Imatinib

ASJC Scopus subject areas

  • Drug Discovery
  • Molecular Biology
  • Biochemistry
  • Organic Chemistry

WoS ResearchAreas Categories

  • Biochemistry & Molecular Biology
  • Chemistry, Organic

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