Preparative synthesis of 2,2-dimethyl-5-(trifluoroacetyl)-1,3-dioxane-4,6-dione (2-trifluoroacetyl Meldrum's acid) and 2,2-dimethyl-6-(trifluoromethyl)-4H-1,3-dioxin-4-one and their synthetic usefulness as (trifluoroacetyl)ketene precursors

Dmitri V. Sevenard, Andrey V. Didenko, Denis Lorenz, Michael Vorobiev, Johannes Stelten, Thomas Dülcks, Vyacheslav Ya Sosnovskikh

Research output: Contribution to journalArticleResearchpeer-review

Original languageEnglish
Pages (from-to)1495-1502
Number of pages8
JournalTetrahedron
Volume73
Issue number11
DOIs
Publication statusPublished - 16 Mar 2017

Fingerprint

Nucleophiles
Dioxins
Cycloaddition Reaction
1,4-dioxane
Meldrum's acid
ketene

Keywords

  • (Trifluoroacetyl)ketene
  • Fluorinated compounds
  • Hetero-Diels-Alder reaction
  • Meldrum's acid
  • Preparative method
  • Trifluoroacetoacetylation

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

WoS ResearchAreas Categories

  • Chemistry, Organic

Cite this

@article{3cec7bfd0dec4332875e593a4a429fb7,
title = "Preparative synthesis of 2,2-dimethyl-5-(trifluoroacetyl)-1,3-dioxane-4,6-dione (2-trifluoroacetyl Meldrum's acid) and 2,2-dimethyl-6-(trifluoromethyl)-4H-1,3-dioxin-4-one and their synthetic usefulness as (trifluoroacetyl)ketene precursors",
keywords = "(Trifluoroacetyl)ketene, Fluorinated compounds, Hetero-Diels-Alder reaction, Meldrum's acid, Preparative method, Trifluoroacetoacetylation",
author = "Sevenard, {Dmitri V.} and Didenko, {Andrey V.} and Denis Lorenz and Michael Vorobiev and Johannes Stelten and Thomas D{\"u}lcks and Sosnovskikh, {Vyacheslav Ya}",
year = "2017",
month = "3",
day = "16",
doi = "10.1016/j.tet.2017.01.065",
language = "English",
volume = "73",
pages = "1495--1502",
journal = "Tetrahedron",
issn = "0040-4020",
publisher = "Pergamon Press",
number = "11",

}

Preparative synthesis of 2,2-dimethyl-5-(trifluoroacetyl)-1,3-dioxane-4,6-dione (2-trifluoroacetyl Meldrum's acid) and 2,2-dimethyl-6-(trifluoromethyl)-4H-1,3-dioxin-4-one and their synthetic usefulness as (trifluoroacetyl)ketene precursors. / Sevenard, Dmitri V.; Didenko, Andrey V.; Lorenz, Denis; Vorobiev, Michael; Stelten, Johannes; Dülcks, Thomas; Sosnovskikh, Vyacheslav Ya.

In: Tetrahedron, Vol. 73, No. 11, 16.03.2017, p. 1495-1502.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Preparative synthesis of 2,2-dimethyl-5-(trifluoroacetyl)-1,3-dioxane-4,6-dione (2-trifluoroacetyl Meldrum's acid) and 2,2-dimethyl-6-(trifluoromethyl)-4H-1,3-dioxin-4-one and their synthetic usefulness as (trifluoroacetyl)ketene precursors

AU - Sevenard, Dmitri V.

AU - Didenko, Andrey V.

AU - Lorenz, Denis

AU - Vorobiev, Michael

AU - Stelten, Johannes

AU - Dülcks, Thomas

AU - Sosnovskikh, Vyacheslav Ya

PY - 2017/3/16

Y1 - 2017/3/16

KW - (Trifluoroacetyl)ketene

KW - Fluorinated compounds

KW - Hetero-Diels-Alder reaction

KW - Meldrum's acid

KW - Preparative method

KW - Trifluoroacetoacetylation

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U2 - 10.1016/j.tet.2017.01.065

DO - 10.1016/j.tet.2017.01.065

M3 - Article

VL - 73

SP - 1495

EP - 1502

JO - Tetrahedron

JF - Tetrahedron

SN - 0040-4020

IS - 11

ER -