Synthesis and antitubercular evaluation on novel 1-ethyl-5-(Hetero)aryl-1,6-dihydropyrazine-2,3-dicarbonitriles and 3-cyano-1-ethyl-5-(hetero) aryl-2(1H)-pyrazinones

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)
Original languageEnglish
Pages (from-to)139-144
Number of pages6
JournalAnti-Infective Agents
Volume14
Issue number2
DOIs
Publication statusPublished - 1 Aug 2016

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Mycobacterium tuberculosis
Salts
Antitubercular Agents
Mycobacterium avium
Nontuberculous Mycobacteria
Isoniazid
Rifampin
Hydrolysis
1,6-dihydropyrazine-2,3-dicarbonitrile
In Vitro Techniques
triethylsilane

Keywords

  • 2(1H)-Pyrazinone
  • Antituberculosis activity
  • Mycobacterium avium
  • Mycobacterium terrae
  • Pyrazine
  • Tuberculosis

ASJC Scopus subject areas

  • Pharmacology
  • Infectious Diseases

Cite this

@article{392f908e1e9f46a0a1373381e774c169,
title = "Synthesis and antitubercular evaluation on novel 1-ethyl-5-(Hetero)aryl-1,6-dihydropyrazine-2,3-dicarbonitriles and 3-cyano-1-ethyl-5-(hetero) aryl-2(1H)-pyrazinones",
keywords = "2(1H)-Pyrazinone, Antituberculosis activity, Mycobacterium avium, Mycobacterium terrae, Pyrazine, Tuberculosis",
author = "Kravchenko, {Marionella A.} and Verbitskiy, {Egor V.} and Skornyakov, {Sergey N.} and Slepukhin, {Pavel A.} and Rusinov, {Gennagy L.} and Chupakhin, {Oleg N.} and Charushin, {Valery N.}",
year = "2016",
month = "8",
day = "1",
doi = "10.2174/2211352514666160728160218",
language = "English",
volume = "14",
pages = "139--144",
journal = "Anti-Infective Agents",
issn = "2211-3525",
publisher = "Bentham Science Publishers",
number = "2",

}

TY - JOUR

T1 - Synthesis and antitubercular evaluation on novel 1-ethyl-5-(Hetero)aryl-1,6-dihydropyrazine-2,3-dicarbonitriles and 3-cyano-1-ethyl-5-(hetero) aryl-2(1H)-pyrazinones

AU - Kravchenko, Marionella A.

AU - Verbitskiy, Egor V.

AU - Skornyakov, Sergey N.

AU - Slepukhin, Pavel A.

AU - Rusinov, Gennagy L.

AU - Chupakhin, Oleg N.

AU - Charushin, Valery N.

PY - 2016/8/1

Y1 - 2016/8/1

KW - 2(1H)-Pyrazinone

KW - Antituberculosis activity

KW - Mycobacterium avium

KW - Mycobacterium terrae

KW - Pyrazine

KW - Tuberculosis

UR - http://www.scopus.com/inward/record.url?scp=84991377749&partnerID=8YFLogxK

U2 - 10.2174/2211352514666160728160218

DO - 10.2174/2211352514666160728160218

M3 - Article

VL - 14

SP - 139

EP - 144

JO - Anti-Infective Agents

JF - Anti-Infective Agents

SN - 2211-3525

IS - 2

ER -