Synthesis and evaluation of antitubercular activity of fluorinated 5-aryl-4-(hetero)aryl substituted pyrimidines

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)
Original languageEnglish
Pages (from-to)3771-3780
Number of pages10
JournalBioorganic and Medicinal Chemistry
Volume24
Issue number16
DOIs
Publication statusPublished - 15 Aug 2016

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Pyrimidines
Mycobacterium tuberculosis
Hydrogen
Substitution reactions
Mycobacterium avium
Nontuberculous Mycobacteria
Russia
Tuberculosis
Outcome Assessment (Health Care)
5-bromopyrimidine

Keywords

  • Antimycobacterial
  • Cross-coupling
  • Nucleophilic aromatic substitution of hydrogen
  • Pyrimidine
  • Tuberculosis

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Molecular Biology
  • Molecular Medicine
  • Organic Chemistry
  • Drug Discovery
  • Pharmaceutical Science

WoS ResearchAreas Categories

  • Biochemistry & Molecular Biology
  • Chemistry, Medicinal
  • Chemistry, Organic

Cite this

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title = "Synthesis and evaluation of antitubercular activity of fluorinated 5-aryl-4-(hetero)aryl substituted pyrimidines",
keywords = "Antimycobacterial, Cross-coupling, Nucleophilic aromatic substitution of hydrogen, Pyrimidine, Tuberculosis",
author = "Verbitskiy, {Egor V.} and Baskakova, {Svetlana A.} and Kravchenko, {Marionella A.} and Skornyakov, {Sergey N.} and Rusinov, {Gennady L.} and Chupakhin, {Oleg N.} and Charushin, {Valery N.}",
year = "2016",
month = "8",
day = "15",
doi = "10.1016/j.bmc.2016.06.020",
language = "English",
volume = "24",
pages = "3771--3780",
journal = "Bioorganic and Medicinal Chemistry",
issn = "0968-0896",
publisher = "Elsevier",
number = "16",

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Synthesis and evaluation of antitubercular activity of fluorinated 5-aryl-4-(hetero)aryl substituted pyrimidines. / Verbitskiy, Egor V.; Baskakova, Svetlana A.; Kravchenko, Marionella A.; Skornyakov, Sergey N.; Rusinov, Gennady L.; Chupakhin, Oleg N.; Charushin, Valery N.

In: Bioorganic and Medicinal Chemistry, Vol. 24, No. 16, 15.08.2016, p. 3771-3780.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Synthesis and evaluation of antitubercular activity of fluorinated 5-aryl-4-(hetero)aryl substituted pyrimidines

AU - Verbitskiy, Egor V.

AU - Baskakova, Svetlana A.

AU - Kravchenko, Marionella A.

AU - Skornyakov, Sergey N.

AU - Rusinov, Gennady L.

AU - Chupakhin, Oleg N.

AU - Charushin, Valery N.

PY - 2016/8/15

Y1 - 2016/8/15

KW - Antimycobacterial

KW - Cross-coupling

KW - Nucleophilic aromatic substitution of hydrogen

KW - Pyrimidine

KW - Tuberculosis

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U2 - 10.1016/j.bmc.2016.06.020

DO - 10.1016/j.bmc.2016.06.020

M3 - Article

VL - 24

SP - 3771

EP - 3780

JO - Bioorganic and Medicinal Chemistry

JF - Bioorganic and Medicinal Chemistry

SN - 0968-0896

IS - 16

ER -