Synthesis, X-ray crystal structure and antimycobacterial activity of enantiomerically pure 1-ethyl-2,3-dicyano-5-(het)aryl-6-hetaryl-1,6-dihydropyrazines

Egor V. Verbitskiy, Maria S. Toporova, Mikhail I. Kodess, Marina A. Ezhikova, Maksim L. Isenov, Marina G. Pervova, Marionella A. Kravchenko, Igor D. Medvinskiy, Sergey N. Skornyakov, Gennady L. Rusinov, Valery N. Charushin

Research output: Contribution to journalArticle

6 Citations (Scopus)
Original languageEnglish
Pages (from-to)247-270
Number of pages24
JournalArkivoc
Volume2014
Issue number5
DOIs
Publication statusPublished - 2014

Keywords

  • Pyrazines
  • Petasis reaction
  • antituberculosis activity
  • extensively drug-resistant and multi-drug-resistant tuberculosis
  • PETASIS REACTION
  • BORONIC ACIDS
  • C-NUCLEOPHILES
  • 1-ETHYL-1,4-DIAZINIUM SALTS
  • ORGANOBORONIC ACIDS
  • PRACTICAL SYNTHESIS
  • MANNICH REACTION
  • O-NUCLEOPHILES
  • SIGMA(H)-ADDUCTS
  • TUBERCULOSIS

ASJC Scopus subject areas

  • Organic Chemistry

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