Highly regio- and stereoselective addition of aminoenones to 2-substituted 3-nitro-2H-chromenes. Unexpected synthesis of 5-(trifluoromethyl)-5H-chromeno[3,4-b]pyridines

Vladislav Yu. Korotaev; Alexey Yu. Barkov; Igor B. Kutyashev; Ivan V. Kotovich; Marina A. Ezhikova; Mikhail I. Kodess; Vyacheslav Ya. Sosnovskikh

doi:10.1016/j.tet.2015.03.041

Highly regio- and stereoselective addition of aminoenones to 2-substituted 3-nitro-2H-chromenes. Unexpected synthesis of 5-(trifluoromethyl)-5H-chromeno[3,4-b]pyridines

Vladislav Yu. Korotaev, Alexey Yu. Barkov, Igor B. Kutyashev, Ivan V. Kotovich, Marina A. Ezhikova, Mikhail I. Kodess, Vyacheslav Ya. Sosnovskikh

Resultado de la investigación: Article › revisión exhaustiva

16 Citas (Scopus)

Idioma original	English
Páginas (desde-hasta)	2658-2669
Número de páginas	12
Publicación	Tetrahedron
Volumen	71
N.º	18
DOI	https://doi.org/10.1016/j.tet.2015.03.041
Estado	Published - 6 may 2015

ASJC Scopus subject areas

Organic Chemistry
Drug Discovery
Biochemistry

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10.1016/j.tet.2015.03.041

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Научная лаборатория «Контролируемого синтеза сложных молекулярных систем»
Сосновских, В. Я., Барков, А. Ю., Коротаев, В. Ю., Мошкин, В. С., Обыденнов, Д. Л., Кутяшев, И. Б. & Усачев, С. А.
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Korotaev, V. Y., Barkov, A. Y., Kutyashev, I. B., Kotovich, I. V., Ezhikova, M. A., Kodess, M. I., & Sosnovskikh, V. Y. (2015). Highly regio- and stereoselective addition of aminoenones to 2-substituted 3-nitro-2H-chromenes. Unexpected synthesis of 5-(trifluoromethyl)-5H-chromeno[3,4-b]pyridines. Tetrahedron, 71(18), 2658-2669. https://doi.org/10.1016/j.tet.2015.03.041

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title = "Highly regio- and stereoselective addition of aminoenones to 2-substituted 3-nitro-2H-chromenes. Unexpected synthesis of 5-(trifluoromethyl)-5H-chromeno[3,4-b]pyridines",

keywords = "3-Nitro-2H-chromenes, Push-pull enamines, Michael addition, Stereoselectivity, Chromanes, Chromeno[3,4-b]pyridines, POTASSIUM CHANNEL ACTIVATORS, ANTIHYPERTENSIVE ACTIVITY, N-NUCLEOPHILES, S-NUCLEOPHILES, 3-NITRO-2-(TRIFLUOROMETHYL)-2H-CHROMENES, 3-NITRO-2-TRIHALOMETHYL-2H-CHROMENES, CHEMISTRY, OXIDES, RING",

author = "Korotaev, {Vladislav Yu.} and Barkov, {Alexey Yu.} and Kutyashev, {Igor B.} and Kotovich, {Ivan V.} and Ezhikova, {Marina A.} and Kodess, {Mikhail I.} and Sosnovskikh, {Vyacheslav Ya.}",

year = "2015",

month = may,

day = "6",

doi = "10.1016/j.tet.2015.03.041",

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T1 - Highly regio- and stereoselective addition of aminoenones to 2-substituted 3-nitro-2H-chromenes. Unexpected synthesis of 5-(trifluoromethyl)-5H-chromeno[3,4-b]pyridines

AU - Korotaev, Vladislav Yu.

AU - Barkov, Alexey Yu.

AU - Kutyashev, Igor B.

AU - Kotovich, Ivan V.

AU - Ezhikova, Marina A.

AU - Kodess, Mikhail I.

AU - Sosnovskikh, Vyacheslav Ya.

PY - 2015/5/6

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KW - Push-pull enamines

KW - Michael addition

KW - Stereoselectivity

KW - Chromanes

KW - Chromeno[3,4-b]pyridines

KW - POTASSIUM CHANNEL ACTIVATORS

KW - ANTIHYPERTENSIVE ACTIVITY

KW - N-NUCLEOPHILES

KW - S-NUCLEOPHILES

KW - 3-NITRO-2-(TRIFLUOROMETHYL)-2H-CHROMENES

KW - 3-NITRO-2-TRIHALOMETHYL-2H-CHROMENES

KW - CHEMISTRY

KW - OXIDES

KW - RING

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JO - Tetrahedron

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ER -

Highly regio- and stereoselective addition of aminoenones to 2-substituted 3-nitro-2H-chromenes. Unexpected synthesis of 5-(trifluoromethyl)-5H-chromeno[3,4-b]pyridines

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