РОЛЬ СИСТЕМНОГО ВОСПАЛЕНИЯ В РАЗВИТИИ ОСЛОЖНЕНИЙ БЕРЕМЕННОСТИ И РОДОВ

Л. В. Соломатина, Ю. А. Журавлева, А. Ю. Бражников, Т. Э. Зубова

Resultado de pesquisa: Articlerevisão de pares

Resumo

The study included follow groups: patients with pre-eclampsia, examined during the third trimester, patients with pre-eclampsia, examined during the first day after labor, patients with hemorrhage during labor above 10-15% of a blood volume without and with hemorrhagic shock. Control group - 24 healthy women. ^mparison group - patients with normal labor. Levels of IL-6, IL-8, IL-10, TNFa, C-reactivity protein, cortisol, myoglobin, troponin I, D-dimers were measured in plasma. On the basis of these markers we calculated, using our own procedure, integrated criterion - scale of SI, ranging 0 to 9. SI was diagnosed only in patients with hemorrhagic shock (76.9%). MODS (50%) and lethal outcomes (29.6%) were detected only in this group too. Meanwhile, SI developed in 100% dead persons and in 84,6% MODS-patients. Pre-eclampsia was attended an increased levels of proinflammatory cytokines and CRP (as systemic inflammatory reaction manifestation), but not other phenomena and SI in whole. The hemorrhagic shock is a damage factor, caused SI development. SI determines state severity, probability of MODS and lethal outcomes.
Título traduzido da contribuiçãoThe role of systemic inflammation in the development of pregnancy and obstetric complication
Idioma originalRussian
Páginas (de-até)111-113
RevistaРоссийский иммунологический журнал
Volume9(18)
Número de emissão1
Estado da publicaçãoPublished - 2015

GRNTI

  • 76.00.00 MEDICINE AND HEALTH CARE

Level of Research Output

  • VAK List

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