The problems of formation and placement of municipal solid waste in the Perm Krai are considered. The lack of temporary storage of waste, the unreasonable organization of selective collection, the unsettled time for export, untimely disposal of waste generated have a negative impact on both the quality of life of the population and the quality of the environment. The problem of waste generation and disposal is considered to be the most acute in modern conditions. At the same time, there is a real opportunity to return them to production, contributing to the partial solution of many socio-economic issues. The paper analyzes the situation on waste management in the Perm Krai, considers various options for the rational use of MSO landfills, provides an ecological and economic assessment of the options for using MSO landfills in the Perm Krai. As scientific novelty of the work, it is possible to note the development of an algorithm for the adoption of organizational and managerial decisions for the selection of the direction of reclamation and use of the territories of MSO landfills.