КЛИНИКО-ЭКСПЕРИМЕНТАЛЬНОЕ ОБОСНОВАНИЕ ВЫБОРА ЗУБНЫХ ПАСТ НА ОСНОВАНИИ МОНИТОРИНГА СОСТАВА РОТОВОЙ ЖИДКОСТИ У ЖИТЕЛЕЙ ЭКОЛОГИЧЕСКИ НЕБЛАГОПРИЯТНЫХ РАЙОНОВ

Vera Molvinskikh, Nadezhda Belokonova, Tat'yana Elovicova , Dar'ya Kiseleva , Maria Chervyakovskaya , Olga Antropova , Olga Olshvang

Результат исследований: Вклад в журналСтатьяНаучно-исследовательскаярецензирование

Аннотация

Жители экологически неблагоприятных районов находятся под влиянием техногенных факторов. Вредные химические вещества поступают в организм из воздуха, питьевой воды, продуктов питания и обнаруживаются в ротовой жидкости, твердых тканях зуба, зубных отложениях, биоптатах тканевых структур и способствуют развитию кариеса и воспалительных заболеваний пародонта. Для профилактики основных стоматологических заболеваний применяются зубные пасты и ополаскиватели. В составе зубных паст содержатся различные абразивы: диоксид кремния, карбонат кальция, диоксид титана, гидрокарбонат кальция, гидроксиапатит, которые могут выступать в роли адсорбентов соединений тяжелых металлов. Биомониторинг с использованием метода масс-спектрометрии с индуктивно связанной плазмой (ИСП-МС) позволяет определять микроколичество металлов в ротовой жидкости. Исследование средств индивидуальной гигиены полости рта показали, что зубные пасты и ополаскиватели, применяемые пациентами для профилактики и лечения воспалительных заболеваний пародонта, имеют адсорбционную активность в отношении ионов металлов. В статье проведена оценка адсорбционной эффективности лечебно-профилактической зубной пасты относительно ионов металлов (хрома, марганца, кадмия, свинца и др.) в ротовой жидкости у жителей экологически неблагоприятных районов. Применение адсорбционно эффективной зубной пасты, содержащей оксиды кремния и титана, дважды в день на протяжении двух недель показало достоверное снижение концентрации ионов марганца, хрома, мышьяка, свинца и кадмия в смешанной слюне жителей, которые находятся под влиянием неблагоприятных экологических факторов. Современный метод ИСП-МС целесообразно использовать для высокоточного мониторинга ионного состава ротовой жидкости пациентов, проживающих в экологически неблагоприятных районах.
Переведенное названиеКЛИНИКО-ЭКСПЕРИМЕНТАЛЬНОЕ ОБОСНОВАНИЕ ВЫБОРА ЗУБНЫХ ПАСТ НА ОСНОВАНИИ МОНИТОРИНГА СОСТАВА РОТОВОЙ ЖИДКОСТИ У ЖИТЕЛЕЙ ЭКОЛОГИЧЕСКИ НЕБЛАГОПРИЯТНЫХ РАЙОНОВ
Язык оригиналаАнглийский
Страницы (с-по)33-37
ЖурналПроблемы стоматологии
Том15
Номер выпуска1
DOI
СостояниеОпубликовано - 2019

Отпечаток

Toothpastes
Fluids
Monitoring
Chemical analysis
Mouthwashes
Metal ions
Chromium
Manganese
Cadmium
Adsorption
Heavy metal compounds
Ions
Tissue
Inductively coupled plasma mass spectrometry
Calcium Carbonate
Biopsy
Silicon oxides
Arsenic
Durapatite
Abrasives

ГРНТИ

  • 76.29.00 Клиническая медицина

Уровень публикации

  • Перечень ВАК

Цитировать

Molvinskikh, Vera ; Belokonova, Nadezhda ; Elovicova , Tat'yana ; Kiseleva , Dar'ya ; Chervyakovskaya , Maria ; Antropova , Olga ; Olshvang, Olga. / CLINICAL AND EXPERIMENTAL SUBSTANTIATION OF THE CHOICE OF TOOTHPASTES ON THE BASIS OF MONITORING THE COMPOSITION OF THE ORAL FLUID IN THE INHABITANTS OF INDUSTRIAL AREAS. В: Проблемы стоматологии. 2019 ; Том 15, № 1. стр. 33-37.
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abstract = "The inhabitants of industrial areas are influenced by anthropogenic factors. Harmful chemicals enter the body from the air, drinking water, food and are found in the oral fluid, hard tooth tissues, dental deposits, biopsy of tissue structures and contribute to the development of caries and inflammatory periodontal diseases. Toothpastes and mouthwashes are used for prevention of major dental diseases. The toothpastes contain a variety of abrasives: silicon dioxide, calcium carbonate, titanium dioxide, calcium bicarbonate, hydroxyapatite, which can act as adsorbents of heavy metal compounds. Biomonitoring using inductively coupled plasma mass spectrometry (ICP-MS) allows to determine the micro-quantities of metals in blood, urine, human milk, hair and oral fluid. The study of oral hygiene products showed that toothpastes and mouthwashes, used by patients for prevention and treatment of inflammatory periodontal diseases, have an adsorption activity for metal ions. The article evaluates the adsorption efficiency of medical and preventive toothpaste relative to the metal ions (chromium, manganese, cadmium, lead, etc.) in the oral fluid of the inhabitants of industrial areas. The use of adsorption-effective toothpaste twice a day for two weeks showed a significant decrease in the concentration of metal ions in the mixed saliva of the inhabitants which are under the influence of unfavorable environmental factors. When using a toothpaste containing silicon and titanium oxides, the concentration of manganese, chromium, arsenic, lead and cadmium ions in the oral fluid decreases within 2 weeks. The modern method of ISP-MS is advisable to use for high-precision monitoring of the oral fluid ion composition in patients living in the industrial areas.",
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CLINICAL AND EXPERIMENTAL SUBSTANTIATION OF THE CHOICE OF TOOTHPASTES ON THE BASIS OF MONITORING THE COMPOSITION OF THE ORAL FLUID IN THE INHABITANTS OF INDUSTRIAL AREAS. / Molvinskikh, Vera; Belokonova, Nadezhda; Elovicova , Tat'yana; Kiseleva , Dar'ya; Chervyakovskaya , Maria; Antropova , Olga; Olshvang, Olga.

В: Проблемы стоматологии, Том 15, № 1, 2019, стр. 33-37.

Результат исследований: Вклад в журналСтатьяНаучно-исследовательскаярецензирование

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AU - Molvinskikh, Vera

AU - Belokonova, Nadezhda

AU - Elovicova , Tat'yana

AU - Kiseleva , Dar'ya

AU - Chervyakovskaya , Maria

AU - Antropova , Olga

AU - Olshvang, Olga

PY - 2019

Y1 - 2019

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