НОВЫЕ ФТОРСОДЕРЖАЩИЕ ПРОИЗВОДНЫЕ 2-МЕТИЛТИО-4-АРИЛАМИНОХИНАЗОЛИНОВ

科研成果: Article同行评审

摘要

A series of novel 4-arylaminoquinazolines based on 2-methylthio-6,7,8-trifluoroquinazolin-4(3 H )-one has been synthesized. It was found that interaction of these compounds with cycloalkylimines leads to the substitution of F7 atom and methylthio group at position 2 retains. 6,7,8-Trifluoro-2-methylthio-4-(2-methoxyphenylamino)quinazoline demonstrated tuberculostatic activity in vitro (MIC 1.5 μg/mL).
投稿的翻译标题NOVEL FLURINE-CONTAINING DERIVATIVES OF 2-METHYLTHIO-4-ARYLAMINOQUINAZOLINES
源语言Russian
页(从-至)437-441
页数5
期刊Журнал органической химии
57
3
DOI
Published - 2021

Level of Research Output

  • VAK List

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